Nuclear Warfare A Conflict of Deterrence - Free Essay Example

Sample details Pages: 7 Words: 2243 Downloads: 3 Date added: 2017/06/26 Category Politics Essay Type Analytical essay Did you like this example? Nuclear warfare is often posited as essentially different from conventional warfare.   Certainly they are conceived of as so, since dominating the cultural imagination in the Second World War (Gamson, 1989, 2).   Dozens of films have been made depicting disasters caused by nuclear war in the past few decades, especially when the threat was most imminent during the cold war, and these films generally depict nuclear weapons as distinct from other violent weapons of war (Perrine viii, 1998). This differentiation is further mirrored in fiction which heavily suggests that psychologically, nuclear weapons are perceived as different and unique.   But does this psychological classification reflect real differences, or are nuclear weapons simply the most dangerous weapon of war on a continuum of deadly weapons?   Examining the history and the policy trends since the first use of the weapons, I argue that nuclear warfare is different not beca use the weapons themselves are deadlier, but because their damage is inflicted on all participants in the war; as a result, nuclear states pursue a policy of deterrence through mutually assured destruction (MAD). To evaluate nuclear war and weapons in comparison with conventional war and weapons and determine their difference, if any does exist, I will use two main criteria.   First, I will examine the violent capabilities of nuclear weapons compared to war fought with conventional weapons and second, I will examine how these weapons are interpreted and used in international relations.   I conclude that the difference between conventional warfare and nuclear warfare is not the weapons themselves, as the damage in terms of destruction of lives, infrastructure, and landscape can be matched by other forms of violence; however, the way in which nuclear weapons perform this violence causes them to be interrupted differently, and this different interpretation means t hat the way political entities view and use them is also different. Nuclear weapons are understood to be distinct from conventional weapons precisely because of their increased destructive capacity, a capacity which negates the goal of warfare.   Here, war is seen as a tactic used for the purpose of gaining power in a struggle between organised political groups. Don’t waste time! Our writers will create an original "Nuclear Warfare: A Conflict of Deterrence" essay for you Create order As such, it is a political instrument, the resort to force to advance political purposes and to settle political conflicts between sovereign communities (Cohen and Lee, 1986, 9).   In a rational political system, in order to go to war, the party waging it must believe that the end result will be conditions so preferable to the pre-war ones that they justify both the risk and the cost of war.   In short, the object of war is to attain a better peace.   Victory in the true sense implies that the state of peace, for ones people, is better after the war than before (Hart 1974, 353).   If nothing can be gained by war, then it is illogical to wage. Because nuclear warfare has the distinct possibility of destroying whole continents, it can be said it is distinct from conventional war. Moreover, the threat of its use can be utilised as an effective diplomatic tool in a way that conventional war cannot really match. This notion provides the foundations behind th e theory of Mutually Assured Destruction (MAD) which assumes that the threat of global devastation is sufficient to deter states from conflict (Sokolski 2004, v). MAD also supports the notion that the possession or development of these weapons gives a state power, however it would be illogical for such a state to utilise them. For example, India views its official defence policy as a doctrine which expressly calls for deterrence by threat of putative retaliation via their nuclear force (Sokolski 2004, 293).   If India were to be attacked by nuclear weapons, so long as India still retained the possibility of striking back with its own weapons à ¢Ã¢â€š ¬Ã¢â‚¬Å" a distinct possibility as the technology stands today à ¢Ã¢â€š ¬Ã¢â‚¬Å" then its counter-attack would be destructive enough to the aggressor as to nullify the original aims.   In short, to a rational actor, nuclear warfare would never be worth the risk, and therefore, it can be suggested that possessing destruct ive weapons is the key to peace. Unfortunately, the counter to this theory argues that nuclear weapons are not a special kind of weapon, and simply function as a deterrent today because they are the latest weapon.   Indeed, there is a history of other weapons which have also been seen as destructive enough to destroy the aims of war.   In the escalation of violence during World War II for example, the attacks on Hiroshima and Nagasaki were only marginally more horrific in terms of destruction of life and property than the firebombing of Tokyo and Dresden which were conducted through the use of so-called conventional weapons (Leviton 1991, 252). Moreover, the holocaust of Nanking by Japan early in the war certainly wrought similar levels devastation though it took the matter of days rather than seconds (Chang 2012, 15). Looking further back into history, civilisation-ending destruction has always been a consequence of war.   When the Golden Horde of the Mongol s attacked the northern Chinese Jin, the most advanced and populated cities in the world at the time, the death toll was in the millions as the Mongols ground the cities into dust.   Moreover, at the time, it also appeared that death on that scale was both unprecedented and unlikely to occur again. The scale of this attack is demonstrated by this account from Arab historian Ibn al-Athir (1160-1233) a tremendous disaster such as [this] had never happened beforeà ¢Ã¢â€š ¬Ã‚ ¦It may well be that the world from now until its endà ¢Ã¢â€š ¬Ã‚ ¦will not experience the like of it again (Burgan 2009, 27).   Looking back even earlier to the Punic Wars, Carthage was destroyed with the Roman equivalent of weapons of mass destruction: salt sewn into the ground to prevent life from ever emerging again (Cornell, 2012, 443).   Biological and chemical pathogens are newer, but equally deadly and fast-acting: mustard gas, for example, became taboo after its effective use for mas s-slaughter by the Germans in World War I (Price 1997, 61). This historical overview shows that the deadliness of nuclear weapons in terms of capacities to destroy civilisations and their civilian populations is not unique. While the decades of research and development since Hiroshima and Nagasaki have certainly amplified the deadliness of the weapons, their capability to kill is not unique. What has changed from the days of Carthage, though, is the speed at which this destruction is done.   This is because a state, once the victim of a nuclear attack, can possibility still retain the ability to launch a nuclear retaliation, and in so doing, create enough to do mass destruction to the victor.   Complete destruction has always been a possible outcome in warfare, but the ability to win a war and still be destroyed to the point that life is no longer sustainable is unique to modernity. As nuclear scholar Cohen writes, a state in a post-nuclear war would not be whi ch political system would survive, but whether any would (Cohen 1986, 9). This categorical difference of MAD makes nuclear warfare an irrational act, waged only by a nihilist system unconcerned with its own existence.   However, these weapons obviously play a role in the international system.   There are two reasons for this.   First, the weapons are not ubiquitous; only a few developed countries have the weapons, giving them a clear military advantage over non-nuclear states.   So long as this advantage remains, deterrence via mutually assured destruction is not possible.   This is one of the reasons which nuclear countries refuse to completely destroy their arsenals; moreover, it becomes a reason for non-nuclear states to pursue such weapons. States will seek to develop nuclear weapons when they face a significant military threat that cannot be met through alternative means (Sagan 2007, 54). Put simply, if two states are in conflict, and neith er possess a weapon which will cause mutually assured destruction, the weaker state will seek such a weapon as an insurance policy.   At the same time, third party states both with and without such weapons will oppose the acquisition, as expanding the nuclear club is only an advantage to the state seeking admittance. Because having nuclear weapons is so important for deterrence, states in possession cannot abandon them nor publically claim that they will not use these weapons.  Ãƒâ€šÃ‚   This how the paradox of nuclear deterrence is reached.   States seeking to avoid nuclear warfare must therefore make a credible commitment to use them; if such a commitment cannot be made, then other states will not be afraid of attacking.   As Cohen summarizes: threatening to do what would serve no political purpose [launch a war of mutually assured destruction] is the only way to avoid nuclear war (Cohen 1986, 10). This principle of nuclear deterrence leads to bri nksmanship behaviour, where nuclear powers continually assert their readiness to use the weapons.  Ãƒâ€šÃ‚   Such behaviour can be observed especially during the Cold War, where the USSR and the USA both threatened nuclear war precisely because they did not wish it to occur.   In the Cuban Missile Crisis, for example, both states demonstrated their willingness to use weapons; it was because their wiliness was so well demonstrated that neither side felt free to use them (Trachtenberg 1985, 142). Had either power capitulated early, the other would have felt free to attack. Since the end of the Cold War, brinkmanship behaviour exists only between actively hostile states.   The USA, not having a serious rival in the unipolar international system, no longer needs to demonstrate its wiliness to use its arsenal.   Where brinksmanship is seen is between states such as India and Pakistan, where both states have reason to engage in conflict and both possess nuclear weapons (Kroenig 2013, 147).  Ãƒâ€š Adding to MAD, there are two other factors which determine nuclear behaviour: psychological categorisation of nuclear weapons as worse and more inhumane than other weapons, and the existence of non-rational actors with the possibility of becoming nuclear powers.   The psychologically distinct category of nuclear weapons arose in part due to the significant pushback against the weapons after the Second World War.   While the violence and destruction caused by the bombs was not significantly worse, as I earlier argued, the newness and manner of destruction caused them to be singled out for condemnation (Tannenwald 2007, 74). As a result, political leaders have come to see them as taboo à ¢Ã¢â€š ¬Ã¢â‚¬Å" that using them or even advocating using them is a breach of ethnics, and that discussing using them in a democratic setting will prohibit election (Wittner 2009, 49). Unfortunately, the existence of a nuclea r taboo creates a problem for democratic politicians who must, by the principles of MAD, continue to pursue brinkmanship behaviour. As a result, a type of doublespeak emerges from nuclear powers.   In order to maintain the image that they are humanitarian and with the added purposes of maintaining relative military power by preventing the spread of nuclear weapons, they must condemn nuclear force.   At the same time, however, these leaders must continually suggest that they are willing to use the weapons if necessary (Bundy 1988, 536). Finally, in the post-September 11th world, nuclear powers have become increasingly concerned with the actions of non-rational or non-state actors who might use not operate by the principles of MAD.   Because non-rational or non-state actors have nothing to lose, they therefore have no reason to prevent them from using such a weapon.   As a result, nuclear policy of the twenty-first century has focused on containing weapo ns of mass destruction (Cirincion 2014, 293).   This focus on containing non-state actors is because, should MAD be properly used against other rational states with comparative military power, these actors represent the greatest threat to the nuclear state. In sum, nuclear warfare compared to conventional warfare is not different in terms of the scale of possible destruction inflicted on the losing state.   However, because the destruction occurs much faster and the losing state is capable of inflicting such a serious blow to the victorious state that negates the entire purpose of war, nuclear warfare is unique.   As a result, the weapons have taken on a psychological taboo as well as a commitment by rational actors not to use them, precisely by threatening to use them.   These powers are also eager to see that nuclear weapons do not spread to new states or non-state actors. It is this paradox that has defined military strategy since the Second World W ar. Bibliography Bundy, M. (1988) Danger and Survival. Random House.   New York. Burgan, M. (2009) Empire of the Mongols. Infobase Publishing. New York. Chang, I.(2012) The Rape of Nanking: The Forgotten Holocaust of World War II. Basic Books. 2012. Cohen, A and Lee, S. (1986) Nuclear Weapons and the Future of Humanity: The Fundamental Questions. Rowman and Littlefield. Totowa, New Jersey. Cornell, T. (2012)The Beginnings of Rome: Italy and Rome from the Bronze Age to the Punic Wars (c. 1000à ¢Ã¢â€š ¬Ã¢â‚¬Å"264 BC). Routledge. London and New York. Gamson, W. and Modigliani, A. (1989) Media Discourse and Public Opinion on Nuclear Power: A Constructionist Approach. American Journal of Sociology. 95(1): 1-37. Hart, B.H. (1974) Strategy. The New American Library.   New York. Kroenig, M. (2013) Nuclear Superiority and the Balance of Resolve: Explaining Nuclear Crisis Outcomes. International Organization67(1): 141-171. Perrine, T. (1998) Film and the Nuclear Age: Re presenting Cultural Anxiety. Taylor and Francis. New York London. Price, R. (1997)The Chemical Weapons Taboo. Cornell University Press. New York. Sagan, S. (2007) Why Do States Build Nuclear Weapons: Three Models in Search of a Bomb. International Security. 21(3): 54-86. Sokolski, H. (2004) Getting Mad: Nuclear Mutual Assured Destruction, Its Causes and Practices. Strategic Studies Institute. Trachtenberg, M. (1985) The Influence of Nuclear Weapons in the Cuban Missile Crisis. International Security. 137-163. Wittner, L (2009). Confronting the Bomb: A Short History of the Nuclear Disarmament Movement. Stanford University Press. New York.

The Yellow Wall Paper By F. Scott Fitzgerald - 999 Words

In the â€Å"Yellow Wall Paper† the main character the narrator tells of her life as she sees it beginning to spiral away from her. She starts to lose her sense of reality and realizes that the life she has been living may not have been one she really was happy with. One of the influences that puts her in the predicament that she is in is her husband John and his sister Jane. Through the narrators eyes we will try see what possible diagnoses could be the cause of her mental illness. What possible treatments could have been used. I believe the narrator definitely suffered from a combination of mental illnesses. One for certain was depressive disorders. There are several forms of depression and many people who suffer from a depressive illness do not seek treatment. But the majority, even those with severe cases of depression, can get better with treatment. Either through medications, psychotherapies, herbalist care, and many other treatments. One form of depression is major depression that can have severe symptoms that interfere with a person’s ability to sleep, work, eat, and enjoy life. Persistent depressive disorder is depressed moods that last for a least two years. Some forms of depression are slightly different, or they may develop under unique circumstances. Psychotic depression can occur when a person has severe depression plus some form of psychosis, such as having disturbing false beliefs or delusions and hallucinations. Which the narrator starts to displayShow MoreRelatedThe Absence of Love10 30 Words   |  4 Pagesand it also paralleled the new way of thinking that still exists today. F. Scott Fitzgerald’s The Great Gatsby is a great representation of how love has become more of a game, in that it is easier to just marry someone who is just as rich as you or in the same social class as yours. 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Peregrine Falcon Free Essays

Introduction: Found among all continents except Antarctica, the Peregrine falcon is a common falcon throughout the globe. When they hunt, they dive from high altitudes and stoop their prey at speeds over 200 miles per hour, making it the fastest animal on the planet. The name â€Å"peregrine† falcon means wanderer and refers to the bird’s long migration path, which has been known to be as far away as 15,500 miles from their original nesting spots. We will write a custom essay sample on Peregrine Falcon or any similar topic only for you Order Now After having a severe drop in Peregrine population during the 1960s and 1970s, this majestic falcon has made a comeback and can be seen throughout many suburban and urban areas of North America. Interesting Facts: * The Peregrine Falcon is on the featured on the Idaho quarter issued in 2007 * Suzuki named the company’s fastest production model, Hayabusa, after the Peregrine Falcon. Hayabusa means Peregrine Falcon in Japanese * Peregrine falcons don’t build nests. They scrape a depression into the soil on the ground or on a ledge, or an abandoned nest that was left behind Map of Region Peregrine Falcon Duck Hawk, Great-Footed Hawk, Wandering Falcon Falco Peregrinus Fact Sheet: * Size: * Body- 14-19 in. * Wingspan- 3. 3-3. 6 ft. * Weight- 18. 8 to 56. 5 oz. * Diet- Starlings, pigeons, blackbirds, jays, shorebirds, waterfowl, bats, and other small mammals * Reproduction: * Number of eggs- 3-4 * Mate once a year * Same partner for life * Nest location- Cliffs or tall buildings * Return to the same spot annually * Name for chicks- eyases * Chicks fledge 42 to 46 days * Time dependent on their parents- Up to 2 months Habitat-All continents except Antarctica * Life span- Up to 17 years Bibliography: * http://www. discoverycove. org/animal-info/animal-bytes/animalia/eumetazoa/coelomates/deuterostomes/chordata/craniata/aves/falconiformes/peregrine-falcon. htm * http://ohiodnr. com/wildlife/dow/falcons/facts. aspx * http://www. raptorresource. org/facts. htm * http://animals. nationalgeographic. com/animals/birds/peregrine-falcon. html * http://www. peregrinef und. org/explore_raptors/falcons/peregrin. html * http://www. allaboutbirds. org/guide/Peregrine_Falcon/lifehistory#at_food How to cite Peregrine Falcon, Papers

Have We Outgrown Our Government free essay sample

Our government Is NOT ruled by a majority, but Instead is ruled by an already enforced set ot laws that are interpreted and enforced on to actions that the government and its people want to participate in: and can only be changed by amending the current list of unalienable laws that are given to us by this Constitution. Even with this understanding, our country still came to this governmental standstill that has threatened to throw us into another. more devastating economic depression. So then we ask, what exactly is wrong with our government? After reviewing articles and isten to Professor Arbours lecture on the advantages to a parliamentary government, [Ve been able to come toa sound conclusion. The Constitutional Republic that we currently have is no longer functional. and that we must adapt and change to a more unicameral, majoritarianistic, parliamentarian system of government, if we wish to see our country thrive as it once did. We will write a custom essay sample on Have We Outgrown Our Government? or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page To understand the root of the problem. we first have to understand the major difference between a unicameral. arliamentarian type of government am arguing for, and the bicameral, constitutional republic that we are currently ruled by. In a parliamentarian system, there iS only one unicameral chamber, Of only ONE political party. The party that is elected has a strong stance, its ideology is well known and can be expected to be followed thoroughly, and it is elected to enact laws and pass legislation. Preferably, the elected party is representative of what the majority of the people actually want. With only one political party, usually housing strong ideologies on what should be done with the country that t is gwermng, It Is much easier for the population to themselves Identify what is working and what Is not orking as law. Addtlonally it is easier tor voters to see where parts ot the system has gone wrong, who implemented these changes, and makes voting out the detrimental unit, either physical representative or piece of legislation, much more effective. Professor Arbours lecture made It a point to drive this particular Idea home, Advantages: Easy for voters to assign blame or credit. Given that elections are able to be held whenever there is a deadlock between representatives as well. this form of government would allow us to quickly handle the dispute by putting it up to a vote. y wanted to force a showdown over the budget a year after the election, wed have another election winning party would get to implement its agenda. In contrast, with the constitutional republic we are in now, assigning blame to parties responsible for malfunctioning pieces of legislation and ousting them from our governing system is one of the most difficult things to do. The fact that our government is run by two different majorities, who seemingly have enough power to be each be respectively called a majority, makes the creation, review, and enactment f laws painstakingly difficult. Taking the current economy, and governmental standoff, of the United States as an example we can see the glaring downfalls of our bicameral chambers unfolding in front of our eyes. With each party blaming the other for economic difficulties, and each claiming to represent their respective groups, no one really knows what exactly these groups really stand for, and consequently, dont know who is to blame for the government breakdown. First of all, as we see that now the parties are becoming more and more united to one central thinking or ideology hey are representing (something that we havent really seen in previous years), this presents a devastating problem towards effective governing of the US. Although we say that the majority rules in our government the fact is that with the amount of power we give the minority group, they do have the ability to act as a majority group would. The group that is considered to be representing the minority group in our population, in efforts to have everyone equally represented, essentially has almost the same amount of power that the majority group has already, in essence, won hrough elections. The article Blame the Constitution for This Mess by Alex Pareene brings this exact point to the forefront: Shouldnt we actually be upset about a system of government that gives 80 people representing 18 percent of the population the ability to drag the United States to the edge of national default? To clarify this even further, the way our governmental system is set up is so disproportionate, that it gives 18% of the population the ability to bring the entire government, including the majority (82% of the US population) to its knees. Through his shocking scenario, one thing remains glaringly clear: our republican system is crippled by the laws that were made to support it. This constant game of strategy to see who can get their bill passed into law, or who can get their specific groups wants expressed to have better chances at re-election takes the focus away from actual effective national governing. This makes our government essentially useless, to the point where it is comparable to two separate groups playing a game of Chicken to see who backs down first. Many people perceive this parliamentary form of government bad, because the ajority would constantly be able to win control over how the government is run. To my understanding, isnt that exactly what we, as a country made up mainly of middle class, working American citizens, so desperately need? This seemingly utopian form of government will undoubtedly have flaws. One said flaw that is quite apparent would be the need to have constant elections, even more frequent that we already legislation that many have viewed as detrimental to the country, there will have to be a vote conducted to decide on it. This would make policy making especially hard, eeing as whenever a policy is made, if it seems detrimental in the eyes of the people, it can be voted out, effectively stalling or making policy making itself, a hassle. Though bothersome, it is a price that I personally would willingly pay if it meant actual representation of our current majority, not representation of ideological minority groups, as stated by Pareene. In my opinion, it has been far too long since policies have sufficiently represented the will of the people, and not the will of the lobbyists at the Capital. This discombobulated Republic that were erroneously call a Democracy has been imply outgrown. We are being run by a government created hundreds of years ago, by men who could have never fathomed what we would become. It is known that a country is not static. Its people, societies, thinking, needs, issues, norms, and ideas are constantly changing and morphing into new, more advance things. Why is it then, that we confine ourselves to a static form of government? If our ideas, needs, norms, and issues are constantly changing, why are we, as a united people, unable to replicate this change in our government? A government that is in charge of running ne of the most prosperous, dynamic, and leading countries in the world, needs to be one that is able to adapt to the changes that, as a country and as citizens, we will inevitably have to face. Over the years, we have become too lax, too fearful to take the reins of our country back. We put the government in power to make sure that order is kept, and to make surer that it will fit our needs, not the other way around. We do not work for our government our government works for us, and with a parliamentarian government, it will have the flexibility to do exactly that. word count: 1,400

Theology Reaction Paper on Hapag free essay sample

A Follower and Believer of God In the film that we have watched entitled Hapag (a Joey Velasco video presentation) I saw and witnessed the different lives of twelve different and poor children. Each of their lives has something special in them, for each life has a special awakening message for us and that is, we must be awakened from the fact that we must just not live our lives not thinking and sharing our blessings with others because we are not alone. Hence, we must not always just consider ourselves first, we must think of others too, because we show that we are good followers and believers of God if we care for others, share our blessings with them and love them, for God is love. For these children, the hardships they have gone through and are going through now are too much. They must not be in that situation because they have done nothing, but for these children who are still young, they are just living their lives the way they wanted to. We will write a custom essay sample on Theology Reaction Paper on Hapag or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page That is their life from day to day, they are already used to it, but they are already suffering emotionally, spiritually and mentally.But what are we doing about it, we do not even mind them, because we think that nothing can change our society having the rich ones, middle ones and the poor ones. We must change that kind of thinking. People must not be judge according to how many money they have. After I have watched that film, I felt sad and at the same time guilty. I felt guilty because I felt that I am one of those people who deprive those children with their happiness. I felt that I must do something. I felt sympathy for them. Also, It did not cross my mind that after watching that film, It would have a big impact on me.I realized things that I did not even mind before. I was just focusing on my personal concerns that I did not mind helping those children. But because of that thinking, I am not living up to what a Catholic Christian ought to do, and that is to do good to my neighbors. Help them. I must show love for them so that they will not feel that they are alone and they will not lose hope and more importantly their faith in God. I remember the part of the film where the poor girl was given teddy bears or toys and not having a second thought, she gave them away.I was touched by what she has done. Even though she could have used those things for her own happiness, she gave them away. She let others have them. She was thinking of others and not of herself. By that selfless act I realized that I have to be selfless too, just like that girl and be sensitive to the people around me to be a better follower and believer of God. Lastly, I may have a convenient life now compared to them but that does not make me superior to them. We are all equal in God’s eye. We are all children of God. No one is ahead of the other.

cons essays

Cloning pros/cons essays In life through mankind has been faced with decisions in science and moving further throughout science. Cloning a new science discovery has taken over the science world and has put questions in many people's heads about cloning actual humans. Would it be such a bad idea? Cloning could be on the brink if modern ideas that could be given rights to be done. In the facts of cloning it has not been possible yet. President Bush has put many restraints on the use of the embryonic stem cells and the testing of them. Cloning humans may not be the best idea because of being moral or immoral. Moreover people have been polled about cloning humans and it has been quoted that it makes them "queasy", but then again you can't stop something from happening once it's been found. Another reason people are uneasy about cloning with using embryos is the "when does life begin?" theory. Some people believe it begins at conception and those who feel that way are not for cloning. Cloning can also be highly inefficient and that cloned calls showed puzzling irregularities; a cloned child would be raised in psychologically murky environment. (Scientific American pg. 34) It is known that if we market ourselves in such a manner- even to fulfill a noble wish, such as the desire to have a child- and place a quantifiable price on the transaction, we have made ourselves into objects whose price is known but whose value has been forgotten. (ProQuest, Shannon, Thomas A.) Perhaps people are trying to market other people, but is this all good? We risk diminishing the value of human life. (ProQuest, Shannon, Thomas A.) People believe that when you create a embryo you've created life, but if you destroy that embryo for science research it's wrong. (Carol M. Ostorm Seattle Times) In several years will it be wrong? Why not use it for reproductive cloning. Could it be the possible way to do any sort of cloning? However cloning may be not such a terrible thing. Bu...

Analyzing The Sopranos First Episode

Analyzing The Soprano's First Episode Perhaps a theme of the first episode of The Sopranos is the idea that even people who do bad things and kill others suffer stress and love their families just like anyone else. This is particularly emphasized with the periodic scenes with the psychiatrist and with the number of times depression is discussed. I imagine the tone of this show to be a dark comedy. As such, I would visually create a dark atmosphere with dim lighting and an overall gray hue. I would also make sure that actors’ performances are not too dramatic or poignant and I would emphasize the physical comedy, such as the scene in which Chris and Big Pussy struggle to get Emil’s body into a dumpster and end up just propping it up against the side. Additionally, sound and music choice has an enormous effect on tone. I would make sure that the accompanying score is light and not too emotional in order to ensure that the comedic aspect of the potentially dark show is not lost on viewers. Because I found the scene, as written, so amusing, I decided to analyze the one describe above in which Chris and Big Pussy try to dispose of Emil. In the show itself, I was underwhelmed by the physical humor of trying to toss the body into the dumpster. It makes realistic sense that the body would not be flung very high, but I imagined it flying higher which, for some reason, seems more humorous to me. As if they almost could have gotten the body in. Seeing the situation, however, it seems a little ridiculous that they’re even trying, which is likely the true intended humor. I found it a shame that they cut all of the rest of the messing with the body (though I notice that throughout the show, they have made many cuts to keep the action and story tight). Aside from this, the actor of Chris does a good job appearing very proud and determined (with his â€Å"sleeps with the fishes† quote) and Big Pussy sufficiently exasperated. This is emphasized by Big Pussy’s la bored breathing. I also found that the line change at the end of the scene shifted the power dynamic a bit. While the script made it seem like Big Pussy felt Chris was beneath him and unworthy of hearing an answer (â€Å"I’m gonna tell you?†) the show’s (â€Å"Why would you even ask that?†) is far less condescending. In terms of camera work, I love the way wide shots establish how high the trash bin is. Additionally, the cut to a shot of the body falling over when Big Pussy explains that there are differences in between the current situation and the one from The Godfather emphasizes the ridiculousness and humor in their own pathetic situation. In this respect, the camerawork allows the full extent of the comedy displayed by the actors to be blatantly obvious for the viewers. If I had to direct someone else in how to maintain consistency for the show, I would begin with maintaining the overall humorous tone. As a suspected before I even watched the episode, having a lighthearted soundtrack is paramount to keeping this dark series comical. Additionally, big contrasts in brightly lit shots and dark, shadowy ones in scenes of â€Å"normal† family fun versus scenes of murder, for example is also key to underscore the dichotomy in the characters’ own lives. In terms of performance, the show also hinges on Tommy successfully executing a depressive, anxious role blanketed by an often false-feeling, almost distracted kind of happiness serving as his self-proclaimed â€Å"sad clown† exterior. Carmela, meanwhile, should be simmering with sorrow, displeasure, and even anger as she watches her family her cheating husband, her distant daughter drift from her. There are a number of plot threads established in this first episode that could grow into a full story. To begin, Carmela’s relationship with her daughter should be followed. Additionally, viewers likely would want to see Tommy continue to visit a psychiatrist and see if the Prozac begins to work. (If it does, it would be good to see how that changes the way he acts.) It would be interesting to see whether Chris will ever earn Tormmy’s respect and then, of course, there’s the question of what Junior plans to do to â€Å"take care† of Tommy.

Analyzing Psychological Disorders Essay Example | Topics and Well Written Essays - 1750 words

Analyzing Psychological Disorders - Essay Example They assert that all disorders stems primarily form learning or conditioning. The major debate that comes out of these two schools is called the ‘Nature v/s Nurture’ issue. In this work, however, I am going to take the stand of biopsychological perspective which attributes biological, psychological and social causes all to be responsible for disorders. In Part A, Schizophrenia will be analyzed in biopsychological perspective. The symptoms, causal factors and drug therapies for the disorder will also be discussed. In Part B, two other disorders, Anorexia and Anxiety will be analyzed again with the aid of biopsychological perspective and other discussions regarding their relevance to the nature-nurture issue and their treatments. While studying the symptoms of Schizophrenia, various researches have found significant difference in the structure of the brain affected by the disorder. Foremost, problems have been found in structural connectivity in the effected brains. The fluid-filled sacs that surround the brain called lateral ventricles were seen enlarged in brains with Schizophrenia. The volume of the brain is reduced and the cerebral cortex is smaller often times (Cazaban, 2003). The blood flow in frontal regions is lower and the temporal lobe is smaller. The hippocampus, amygdala and limbic system are also found to be smaller by certain researches (Cazaban, 2003). The major part of the brain affected by this disorder is the prefrontal cortex which is associated with memory that results in the disordered though. A major causal factor of Schizophrenia is described to be genetic. A number of recent studies have confirmed that this disorder can be genetically transferred. There is a strong association between the closeness of the blood relationship (i.e. level of gene sharing or consanguinity) and the risk for the disorder (Carson, Butcher, Mineka, & Hooley, 2007 p.501). Several other twin-studies conducted also confirm that people are genetically

Theory of Multiple Intelligences Research Paper Example | Topics and Well Written Essays - 750 words

Theory of Multiple Intelligences - Research Paper Example Such test scores would then be inferred against a predetermined rating which is supported through statistical techniques. The statistical techniques relate the responses issued by the subjects of different ages. The relating of the scores across ages and across various tests is based on the notion that intelligence is constant and does not change age experience or training (Gardner, 2006). In other words, intelligence is an inborn characteristic of individuals. Gardner pluralized the traditional intelligence concept leading to a new definition and educational approaches. Intelligence becomes the ability to process a specific kind of information. This ability originates within the humans psychological and biological make up (Gardner, 2006). These intelligences consist an ability to solve problems of create products that are a result of one’s cultural and community settings. Gardner came up with eight intelligences, which are linguistic intelligence, logical-mathematical intelli gence, spatial intelligence, bodily-kinesthetic intelligence, musical intelligence, interpersonal intelligence, intrapersonal intelligence, and naturalist intelligence. Musical intelligence involves sensitivity to music. It is evident through sensitivity to tones, sounds, rhythms and other musical components. According to Gardner (2006), people who have this intelligence have the ability to compose music, sing and play musical instruments. They have a good pitch and sometimes an absolute pitch. Bodily- kinesthetic intelligences involve the capacity to use one’s entire body or parts of the body to handle challenges. One uses mental ability to coordinate body parts/movement to solve problems (Smith, 2008). Logical-mathematical intelligence comprises of the ability to perform logical analysis of problems, conduct mathematical calculations and examine phenomenon scientifically. The individual can reason deductively, detect patterns and thinking logically. It is often associated w ith mathematical reasoning (Smith, 2008). Linguistic intelligence is characterized by sensitivity to language, both spoken and written. It concerns the ability to acquire or learn languages, and us a language to achieve certain goals (Smith, 2008). This includes ability to use a language as a means for remembering information, and ability to express oneself poetically or rhetorically using a language. Examples of people with these skills include lawyers, poets, speakers and writers among others. Spatial intelligence, on the other hand, comprises the capacity to identify and utilize patterns of open space and confided areas. Interpersonal intelligence is people oriented intelligence, which is consists ability to understand other people’s desires, motivations and intentions. It facilitates coexistence of people. As Smith (2008) Notes, salespeople, counselors, political and religious leaders, and teachers thrive on strong interpersonal intelligence. Intrapersonal intelligence is made up of the ability for self awareness. It involves understanding oneself and appreciating personal feelings, motivations and fears. It also entails developing a working model of ourselves and ability to use such models for self regulation purposes (Smith, 2008). Finally, naturalistic intelligence

Analysis of Green Mountain Coffee Roasters Essay Example for Free

Analysis of Green Mountain Coffee Roasters Essay Introduction Green Mountain Coffee Roasters (GMCR), a leader in specialty coffee and coffee makers, was founded in 1981 by Bob Stiller (Green Mountain Coffee Roasters [GMCR], n. d.). From a small cafà © to a company listed on NASDAQ and then to a company with more than $2.6 billion net sales revenue by Sep 24 2011 (GMCR, 2011), GMCR enjoyed great financial successes. Besides, it has been recognized consistently as a socially responsible company. Key Factors in GRMC’s Success After studying GMCR case, several key points are identified which together contribute to the success of GMCR as both corporation and corporate citizen. First, GMCR convenes members from all parts of its system for important company activities. In many companies, most of the staff in the lowest level of organizational structure are excluded from company activities. But representatives from GMCR’s whole system get together in its annual summit meetings (Mary 2008). The get together is useful in helping its participants better understand their importance within the organization and realize they can do more to better serve the system. People from all parts of GMCR also go to training programs (Mary 2008). These programs are a platform for staff to learn necessary knowledge with which they can better serve the customers. Including members from all parts of the system gives them a sense of personal involvement which encourages them to align their own interest with that of company. When employees feel that they are truly part of the organization, they tend to internalize the needs of the company rather than just treat their jobs as externally imposed obligations. They may also find their job meaningful and pleasant, have a stronger feeling of belonging and eventually are likely to work harder and exhibit increased labor productivity. In a nutshell, Bob Stiller makes all members truly participate in his venture and sparkles their potentials to better serve GMCR. Bob Stiller also take employees from different parts of the company to coffee farms(Mary 2008). Therefore employees can have personal experience about coffee farming which may increase their awareness and attention. For example, roasters may learn that lots of hard working is needed to harvest organic coffee bean and hence may pay more attention when roasting coffee bean which cause less waste of bean. Second, GMCR’s decision making process is based on the interest of all stakeholders rather than the company itself. For example, GMCR works to add social value by engaging in education programs for the children from farming families and communities (Mary 2008). Assisting these children builds stronger relations between GMCR and its farming families. GMCR also provides interest free financial resources to the farmers (Mary 2008), which eventually results in smooth supply of high quality bean. By taking all members’ interest into account, Bob Stiller builds a strong, desirable and sustainable network with all members within the system, which in turn supports the growth of GMCR. Third, GMCR has committed to organic coffee and creates social value by offering a much healthier lifestyle. Besides, GMCR’s success sets an example for other companies want to join organic market. GMCR improves environment by protecting coffee farm from the bad impact of chemicals and assuring the future generations a viable farm (Mary 2008). It is difficult for farm owners to keep coffee trees alive as long as possible (Mary 2008) and the support from GMCR makes it possible. Therefore farmers are able to make a living out of coffee beans, and more importantly, they have a higher satisfaction because they can preserve and pass the farm to their future generations(Mary 2008). GMCR’s partnership with its farmers not only guarantees a smooth bean supply but also increases farmers’ spiritual wealth and again strengthens their relations. For trade-off problems, Bob Stiller always adhere to â€Å"future thinking† (Collins Porras, 2002), making decisions based on long term benefits for the whole interconnected system rather than GMCR itself. Besides, Bob Stiller has committed to creating wealth which not only incorporates financial value but anything brings value to the whole system and the whole society. References Collins, J., and Porras, J. I. (2002). Built to Last: Successful Habits of Visionary Companies. New York: Harper Business Essentials. Green Mountain Coffee Roasters. (n. d.). Corporate review. Available at http://www.gmcr.com/about-GMCR.html, accessed August 24, 2012. Green Mountain Coffee Roasters. (2011). Consolidated Statements of Operations. Green Mountain Coffee Roasters Inc. Form 10-K. Available at

Free College Essays - The Last Act of Richard III :: Richard II Richard III Essays

The Last Act of Richard III In Shakespeare's play Richard III, the main character Richard is developed as an actor - to the degree of morbidity. Richard is forever putting on an act, and playing the part that he thinks will most please whomever he shares the stage with at a given moment. Not that to please is his ultimate goal, it is just a means to get what he wants--which is the tempting role of the king. His acts are from the start plentiful, and for some time almost surprisingly effective. To Clarence he plays the Loving and Concerned Brother. His counterfeit fools Clarence into a state of trust that is stunning to the spectator, who knows that the events which make Richard exclaim "We are not safe, Clarence, we are not safe!" (I.i.70) are in fact Richard's own doing. Alone with his audience, Richard plays the part of the Self-confident Villain. The audience serves a function not unlike that of a mirror, only it mirrors character traits rather than looks. He introduces himself as the actor who cannot play the role of lover (i.e. be good) satisfactorily, so he chooses to play the villain (i.e. be bad) instead. The notion that this is a choice, as well as his use of the word play rather than be, underline the fact that to him this is all acting. In front of the audience--his mirror and thus a second self--Richard toys around with the conviction that he can do anything he sets his mind to through the means of his acting abilities. He leaves his audience speechless by going through with the overly ambitious task he sets up. He tells us that he will marry Warwick's youngest daughter, and the next thing you know, he has pulled it off. Whether Anne falls for Richard's sex appeal or his rhetoric is moot, yet she does fall. Richard himself seem s credulous at her giving in so easily; "Was ever woman in this humour woo'd? / Was ever woman in this humour won?" (I.ii.232-233) He talks as if it were a sign that his repulsiveness must in some way appear attractive to her, although the way he expresses this makes me doubt his seriousness. Perhaps this is an attempt at sharing a joke with his audience, his feeling being that as it cannot possibly be his looks she has fallen for, it must be his words.

Nike and Human Rights Essay

1. What ethical issues faced by MNCs in their treatment of foreign workers could bring allegations of misconduct in their operations? †¢Ethical issues may include the violation of fundamental human rights of ‘sweatshop’ workers such as freedom, speech and discrimination. The treatment of their workers could be deemed ‘unethical’ by media who construe this view to consumers. Such allegations can and will have damaging effects with Nike having been taken to court already in the past. 2. Would the use of third-party independent contractors insulate MNCs from being attacked? Would that practice offer MNCs a good defensive shield against charges of abuse of â€Å"their employees†? †¢Not necessarily, as Nike will be using labour which is just managed by another party. They would just be shifting the blame of abusing â€Å"their employees† to hiring someone else’s. The connection of the brand to any unethical labour will still be damaging regardless of whether they are directly related or not. 3. Do you think that statements by companies that describe good social and moral conduct in the treatment of their workers are part of the image those companies create and therefore are part of their advertising message? Do consumers judge companies and base their buying decision on their perceptions of corporate behaviour and values? Is the historic â€Å"made in† question (e.g., â€Å"Made in the USA†) now being replaced by a â€Å"made by† inquiry (e.g., â€Å"Made by Company X† or â€Å"Made for Company X by Company Y†)? †¢I think that good social and moral conduct is an inaugural part of the advertising and marketing message of any brand. In these times more consumers are moving to seek ethically sourced products (such as fair trade coffee), this includes worker conditions and perceptions the consumer may have of the company’s corporate activities. The ‘made in’ question is not necessarily being replaced by ‘made by’ it is more likely that both questions are beginning to be asked in conjunction with one another. 4. Given the principles noted in the case, how can companies comment on their positive actions to promote human rights so that consumers will think well of them? Would you propose that a company (a) do nothing, (b) construct a corporate code of ethics, (c) align itself with some of the universal covenants or compacts prepared by international agencies? †¢It would be wise for Nike to develop a corporate code of ethics to help foster what is seen as acceptable standards within the company and its operations. It would also be beneficial to comply with international practice standards. 5. What does Nike’s continued financial success, in spite of the lawsuit, suggest about consumers’ reactions to negative publicity? Have American media and NGOs exaggerated the impact of a firm’s labour practices and corporate social responsibility on its sales? How should managers of an MNC respond to such negative publicity? †¢Nike’s continued success suggests that consumers may not be as deterred by negative publicity as it has been suggested. Nike still remains one of the biggest global brands today and perhaps the value of the label is stronger than damaging publicity. American media and NGOs may have sensationalised the impact of CSR on sales to some extent, although it is deemed important by some consumers, it seems that demand for Nike good remains strong regardless as many are more swayed by celebrity endorsements than working conditions. Managers of MNCs should respond to unfavourable publicity fixing the exposed issue, undertaking community outreach programs, and implementing pre-emptive measures to ensure that bad publicity will not be an issue in the future.

Explain how act 1 scene 1 prepares the audience for the actions that follow

Act 1 scene 1 main purpose is to introduce the themes in the play, preparing the reader for the conflict between the contrasting outlooks of the characters. In the first scene we see the friendship groups between the characters also showing the potential ‘lovers' from this initial description, Finding out who is friends with who can also give us explanations to who is going to defend each other and who may want to maliciously trick each other. Shakespeare also shows opposing traits between many characters, even between family members. Hero is polite, quiet, respectful, and gentle, whereas Beatrice is feisty, cynical, witty, and sharp. Similarly there is a contrast between Don John who has evil and deceptive intentions, and his opposite, Don Pedro, who is a loyal and noble person. Don John ‘the bastard' and his vile comrades contrast with Don Pedro the noble prince and his heroic friends. The difference in the brothers' standing in society is mirrored in their personalities. In the first scene, we see an apparent reconciliation between Don John and Don Pedro but the jealous and malicious instincts of Don John can not hide themselves for too long â€Å"I can not hide what I am†, he confesses â€Å"I am a plain dealing villain†. It is ironic how frank Don John is about his character, as many of the protagonists deceive each other, and in Beatrice and Benedict's case they trick even themselves into believing â€Å"I love none†. Deception is a recurrent theme, not only this play but also many of Shakespeare's plays. You can read also Audience Adaptation Paper Hero is a conventional, â€Å"modest young lady†, different in both appearance and personality to her cousin Beatrice. Hero conforms to the patriarchal society of Messina, obeying her father unquestioningly, and behaving demurely, like a woman ‘should'. Beatrice is older than Hero, yet unlike her cousin she is unwilling to conform. Feisty and assertive, Beatrice engages in intelligent wordplay, a ‘merry war' with her male superior, Benedick, referring to him as â€Å"signor mountanto† a fencing term symbolic of the battle of words and wills the two share. Though their insults are biting, their ability to maintain such clever, interconnected sparring seems to illustrate the existence of a strong bond between them. The audience is prepared for the great contrasts in behaviour between the two women from the start of the play, and begins to expect a resolution involving the ‘taming' of Beatrice. We can also assume by Benedick`s description of Beatrice that he does in fact find her more attractive then we first thought and he ‘accidently' reveals he is attracted to Beatrice in comparison to that of Hero, she â€Å"exceeds in beauty†. This is also Benedick showing rudely how â€Å"I do not like (Hero)†. Beatrice and Benedick are perhaps Shakespeare's most famously witty characters; neither lets the other say anything without countering it with a pun or criticism. First impressions of Benedick are of loyalty to his friends, but also of arrogance and he sounds on the outset like a misogynist, proclaiming â€Å"I am loved of all ladies† but â€Å"truly I love none†. As the scene progresses we get small inclinations that maybe he does love someone, â€Å"her cousin exceed her as much in beauty†, showing he finds Beatrice attractive. He engages with Beatrice in a competition to outwit, outsmart, and out-insult the other. As with many of Shakespeare plays we can presume this ‘merry war' is hiding their true feelings. From first impressions we see he is constantly performs for the benefit of others, and indulges in witty banter with many to express his feelings. Claudio from the beginning seems deeply attracted to Hero, showing a romantic outlook with â€Å"soft and delicate desires†. Unfortunately, his fickle and suspicious nature makes him quick to believe evil rumours, and he is hasty to despair and take revenge. He appears to love Hero, but the opinion of others changes his mind so we have to question if this relationship is genuine. It is also strange for us to see his love so quickly in the first scene, as he first notices â€Å"the sweetest lady I ever looked upon†. Don Pedro insists on wooing Hero for Claudio himself, whilst masked, rather than allowing Claudio to profess his love to Hero first, â€Å"I will assume thy part in some disguise†: this is the first introduction to the recurrent theme of appearance and reality.

Mexico and America; Ethnic Groups and Discrimination

Mexico and America; Ethnic Groups and Discrimination Free Online Research Papers Mexicans immigrated to the United States back in the 1800’s (Stanford, 2006). In 1848 the United States took over a part of Mexico which is not the Southwest (which is where I’m from, The Rio Grande Valley). Hispanics living in these areas were Mexican citizens before the acquisition. The United States even went into agreements with Mexico to have Mexicans work in the United States. Mexicans were treated with cruelty, while working the agricultural fields for years. The United States made several agreements with Mexico to have the Mexicans come to work in the US while American soldiers were fighting in the world wars. The labor shortage that the United States went through was reason enough to have Mexicans migrate to the United States as laborers. The United States found there was a need to have Mexicans come fill in for the labor shortage but they were no longer needed during the depression of the US. Not only were Hispanics send back to Mexico, but Mexican-Ame ricans were sent back as well because they were no longer needed. My culture has suffered from prejudice and several other discriminations such as the dual labor market, redlining, affirmative action and reverse discrimination. Mexicans suffered from the dual labor market even though employment was offered to Mexicans during the shortage of labor that the United States was going through, no safety was provided to the workers. No insurance was available for the laborers either. The United States was prejudice towards Mexicans because as soon as there was no need for their labor services they were sent back to their country. Everyone who was brought to the United States to work including the Mexican-Americans, who were citizens of the United States, was sent back to Mexico. Why were the first colonists not sent back too? Mexicans used to live in what is now the Southwest before it became part of the United States. Not only was my culture robbed from their rightful land but no benefits were given to them while assisting the United States with their shortage. Have you ever heard the phrase, â€Å"Everything is bigger in Texas.†? Texas is the largest state in the United States. The majority of residents in Texas are Mexicans. Mexican Americans are not the minority in the state anymore and discrimination occurs in several hidden ways. We have come a long way and diversity is practiced throughout the work place. It will continue as long as society continues to compare ethnic groups. Yes we are all different, and we should be proud of who we are, but are we all not human? Redlining used to happen and is still happening. â€Å"Mexicans will not be able to purchase their own homes much less be the owner of a new vehicle.† This type of comments is patterns of discrimination that Mexican-Americans have faced at one time or another. I, myself, have encountered this type of discrimination several times before. Rather it is at school or at work. I drive up in a new vehicle and I have heard people make comments about how it cannot be mine! The affirmative action took place when the minority groups were given the opportunity to get jobs (Schaefer, 2006). Although in Texas and in some other states Mexican Americans are not the minority, the ethnic group overall is still a minority; therefore the group has faced and endured the affirmative action. Presently there is still some social inequality and reverse discrimination is something that I have faced. Some places exist where they will not hire someone if they do not know how to speak Spanish even though English is the main language at the work place. They can easily get away with it because they report that the language is needed to conduct the business and this is accepted by the United States Equal Employment Opportunity Commission. With this in mind there will always be hidden ways discrimination will present itself. The world seems to have improved throughout the years but there will always be a certain someone who did not learn from the mistakes. Mexican-Americans are not the only minority in this country and all other minorities have faced some sort of discrimination as well. This has always been a touchy subject, why can’t people get along with each other? I think it’s about time we all tried! The world would be a better place if we learn to accept each other’s differences and learn to appreciate each other, and understand that we are all equal. ? References: Schaefer, Richard. (2006). Racial and Ethnic Groups. [Axia College Custom Edition e-text]. , : Prentice-Hall. Retrieved August 29, 2008, from Axia College, ETH 125 Cultural Diversity Web site. Stanford, E. (2006). Interracial America. Opposing Viewpoints Resource Center Detroit: Greenhaven Press. Retrieved February 15, 2008 from Gale. Apollo Library. http://find.galegroup.com/ips/start.do?prodId=IPS www.ask.com. (2008). Hispanics in America. Retrieved August 29, 2008, from www.ask.com Google. (2008). Hispanics in America. Retrieved August 29, 2008, from www.google.com Research Papers on Mexico and America; Ethnic Groups and DiscriminationThe Effects of Illegal ImmigrationNever Been Kicked Out of a Place This NicePersonal Experience with Teen Pregnancy19 Century Society: A Deeply Divided EraAssess the importance of Nationalism 1815-1850 EuropeBook Review on The Autobiography of Malcolm XTwilight of the UAWPETSTEL analysis of IndiaMoral and Ethical Issues in Hiring New EmployeesAnalysis of Ebay Expanding into Asia

Supply Chain Management Issues in Boeing Essay Example | Topics and Well Written Essays - 3000 words

Supply Chain Management Issues in Boeing - Essay Example This has also put all other stakeholders into serious problems. This paper presents an analysis of the supply chain of Boeing in the context of various facets of the management of the supply chain by the company. In response to A 380 airliner from its arch rival Boeing Corporation embarked on the manufacture of 'Boeing787 Dreamliner' a light weight model with seating capacity of 210 to 296 passengers. "The 787 Dreamliner is a family of new airplanes that promises to bring big-jet comfort and economics to the mid-size market. The Boeing 787 incorporates advanced materials, systems and engines to provide a 20% improvement in fuel performance on a per-passenger basis. The 787-8 Dreamliner will carry 210 to 250 passengers about 7,650 to 8,200 nautical miles and the 787-9 will carry 250 to 290 passengers about 8,000 to 8,500 nautical miles (Boeing Commercial Aerospace). The first delivery was scheduled for May 2008 which now has been pushed as far as the second quarter of 2009. With firm orders worth $ 144 billion the company has found serious issues with its global supply chain as a result of which the company has postponed the delivery of the airliner a number of times causing serious concerns to the major airlines that have placed orders with Boeing for this aircrafts. The production process of making the new aircraft with new light weight composite materials in itself is a challenge for the company. In addition the company has made drastic changes in its supply chain which eventually has hit the progress in the manufacture and delivery of Dreamliner. The way in which the company has organized its supply chain for 787 manufacturing has put a complicated way in which the supply chain partnering firms share risks and profits from the airliner. This implies that the financial burden will be put up and down on the firms in the chain as every company would like to protect their own financial interest. This would necessarily result in chaos in the short-term and considerable delays in the completion of the manufacture of the product which will make everyone in the line suffer. The real issue is Boeing attempted to use what appears to be an automotive product like production pr ocess in which all the parts and components in a pre-fabricated form are brought the assembly line. This has necessitated sections of the aircraft to be flown out of far off locations in Japan, Italy, South Carolina and Kansas to be assembled in Washington within a short time of as much as three days. Apart from this there are various other supply chain issues being faced by the company which are explored by this paper. Boeing and Supplier Quality Management Manufacture of Boeing 787 Dreamliner represents a complete shift in the manufacturing philosophy of Boeing Corporation as the company

Education by Postcode Essay Example | Topics and Well Written Essays - 1500 words

Education by Postcode - Essay Example (58) Hence as a result, the modern society's realization of the fact that education is indeed a vital part of human development, it could not be denied that experts on the matter never stop finding better ways to assist human individuals [both young and old] to realize their capabilities and the opportunities available for them to learn more and be able to have better use of their time as well as to have better future ahead of them. It could be noted education then is drawn even closer to the learners so as to assure that the said individuals would not loose their interest in the matter simply because of the not being able to handle the matter considerably for certain reasons. (Vandergrift, 1992, 58, 59) In some faraway places, say for example distant areas that are found around the suburbs, universities and other he facilities for learning are at times absent in the area. Hence, as a result, only a few among those living in such areas are able to get access to the most effective educati on that they deserve. To be able to cater to these students, the experts found better systems of learning that would be most effective for the learning of the said individuals. ... Most of these educational forms take place through the Internet. Botelho (2004) describes the matter as a process that involves high tech gadgets as means of connection between instructors and students which include a hooked up video conferencing may best be used in this course of learning thus virtually connecting the learner to the instructor's care. (Internet) It is undeniable that through the said process, students are given the chance to learn normally even though they are not physically present in class. (EET, 2007, Internet) The said process is still classified as part of the postcode system of education because the process still involves snail-mailing the results of exams, provision of some school materials (such as books and other materials of the same kind) that the students may need for learning. Through this, the student would have soothing tangible out of the system that he or she chooses to learn from. Vandergrift (1992) further adds that education, as known is very much significant for the human society as this is viewed and considered as the most efficient and effective means for personal and social development among human individuals. (58) The concept of education entitles an individual, if properly trained and utilized the essential ability to progress for personal sustenance and economic survival. This is considered as one of the most important realm in one's life that must be achieved by each and everyone in the society. In addition, education can be used by the society as a whole to developed productive and capable citizens for fueling the progress of the humanity. Thus, education indeed is important. In the present

The Impact of Apple Devices on Society Research Paper

The Impact of Apple Devices on Society - Research Paper Example From the discussion it is clear that Apple Inc is a renowned America-based multinational conglomerate operating in software as well as hardware industry. The head office of Apple is situated in Cupertino in the region of California. It was established in the year 1976 by Steve Jobs, Steve Wozniak, and Ronald Wayne. It possesses in its assortment variety of products such as iPod, iTunes, iPhone, Apple TV, Mac accessories, and software to gratify customers’ desires. There are about 364 retail stores of Apple operating to present excellent products and /or services to its customers. In addition, the company employs approximately 60,400 employees across the globe to maintain its operations in an efficient way. As the paper highlights Apple has offered more attention to the facet of constant research and development to present various types of innovative products to the people. It facilitated Apple to expand its market share and profitability by a considerable extent. Moreover, it also improved the total sales of its products, thereby amplifying its supremacy in the market as portrayed in the figure below. The sales growth of the products of Apple is also shown in the below diagram, which reveals that the citizens across the globe highly prefer the products of Apple. In fact, the demand and the supremacy of the products of Apple amplified in recent years. Apple is recognized as one of the most successful brands in software market across the globe.

Opression and Inequality Essay Example for Free

Opression and Inequality Essay â€Å"Racism, Oppression, and Inequality within The Welcome Table and Country Lovers† In this paper I will analyze the similarities and differences between Country Lovers written in 1975 by Nadine Gordimer, and The Welcome Table written in 1970 by Alice Walker. The overall theme and concept between The Welcome Table and Country Lovers are racism, oppression, and inequality which I analyze with critical thought and precision. Before I can begin to draw any conclusion as to comparing and contrasting the two stories Country Lovers and The Welcome Table, I must first familiarize myself to several important concepts of each story. These important concepts consist of the plot, theme, list of characters involved, the setting, the style, and the tone of the narrator. Also, what method does the narrator utilize to gain and keep the attention of the reader at a maximum level? The Welcome Table, written by Alice Walker, is one of the most enjoyable and inspiring pieces of literature I have ever read. The Welcome Table’s style is formatted in the third person point of view, but frequently shifts throughout the story. The beginning or the first part of the story is told strictly from the white people’s perspective as they witness an elderly black woman nearly blind, with a lean build and grayish tone to her skin enters their church. The historical development of the African-American woman can be traced within the African-American literary tradition while locating religion as a central influence of her strength character, and dedication (LaGrone, 2009). The author does a superlative job enhancing the story by incorporating such a descriptive nature to the characters. Particularly the main character which was described by her attire as being an old mildewed black dress with missing buttons and a greased stained head rag covering her pigtails. The elderly black woman was further described as having blue-brown eyes with very wrinkled skin. It was also mentioned of how profusely perspiring the elderly black woman was 2 1 2 1. plot, theme, list of characters This sentence is not balanced or parallel. For example, incorrect: The child spent the day singing, dancing, and played in the sandbox. Notice that played is not parallel with singing and dancing. Correct: The child spent the day singing, dancing, and playing in the sandbox. Example: Plot, theme, characters, etc. [Monique Sheffield] 2. The historical development of the If this is a direct quote it should be in quotation marks. However, the quote doesnt support wat you are saying. Consider either using another quote that support what you stated or adding more information that leads up to your quote. [Monique Sheffield] RACISM, OPPRESSION AND INEQUAL 3 when she arrived at the church, which in my opinion illustrates the fatigue and the struggle in which she endured. By incorporating vivid elements of descriptive images, the author made it rather easy to unite with this amazing journey. The race problem is not really an issue of cultural deficiency, racial bias, or structural dislocation. The race problem is an issue of power (Kuykendall, 2005). The story continued in the white people’s perspective after she took her seat, more directly pertaining to the usher who was informed to tell the elderly black woman to leave. The point of view switches to the white women inside the church, due to the fact the white women took it as a personal insult. The constant back and forth changing of the narrator in my opinion, heightens the intensity and emotional depth to this literary work. The narration of the story changed once again to the spouses of the white women who felt as though they were insulted by the mere presence of the elderly black lady. The white men followed the instructions that were given and aggressive with force threw the elderly black woman out of the church. After the elderly woman is thrown out of the church the narration switches back to the main character of the story. The truth is that until we can understand the pain we inflict on each other because of hatred and exclusion, we will never fully understand why racial reconciliation is so essential to the future of American (Waller, 2000). The next episode or set of events introduces the climax in the story. According to Clugston (2010) the climax of a story is the high point of tension that becomes the turning point in which the outcome is determined. We must strive to reinterpret the sociopolitical dynamics of race, to free the mind and heart as much as possible from the mistakes of the past (Winant, 1994). In my opinion the elderly woman’s turning point was the arrival of Jesus. To those of us who believe in 3 1 2 1. which in my opinion illustrates In a comparison/contrast paper keep your opinion out. You are not writing an opnion paper. [Monique Sheffield] 2. The race problem is not really Again, your quotes are not fitting the paper. If you need assistance incorporating sources into your research paper, select the â€Å"Library† tab on the left side of your online classroom. Next, go to Tutorials Sources Incorporating Sources into Your Research Paper. This video focuses on how to effectively incorporate sources into your research assignment. [Monique Sheffield] RACISM, OPPRESSION AND INEQUAL 4 Jesus Christ just as the elderly woman it was truly an epiphany. An epiphany is defined as a profound and sudden personal discovery (Clugston, 2010). After her visual image became clear, and she realized who it was, she started jumping about and slapping her hands on her knees. This is an example of the overwhelming joy and excitement she was experiencing. Jesus was described as wearing an immaculate white, long dress trimmed in gold around his neck and hem, and a red, bright red cape. He was also wearing sandals and had a beard which was centered upon his long brown hair. This statement once again illustrates the profound descriptive nature of the story which contributes to the story’s appearance. According to Clugston (2010), simile is defined as a direct comparison of two objects that are similar in at least one aspect, using like or as to link the similarities. In this particular event the author referenced the face of Jesus Christ to that of a glowing candle. His steps were mentioned to be â€Å"sure† and â€Å"perfect† as if He was walking on the sea. As the elderly woman and Jesus began to walk together she started to tell Him about the many years she took care of them, cooking, cleaning and nursing. We have pursued the shadow, they have obtained the substance; we have performed the labor, they have received the profits; we have planted the vines, they have eaten the fruits (1,200). This excerpt of oppression and injustice was felt by the elderly woman. After releasing all of her frustrations, cares, and problems Jesus smiled at her and instantly she felt as though a burden had been removed. The burden of the elderly woman reflects the theme of the story which is a combination of racism, oppression, and inequality. Another descriptive comparison was related to the ground Jesus and the elderly lady walked on, it was compared to walking on the clouds. A very interesting ending occurred in this story; no one actually knew what happened to the elderly woman. There came about many speculations. The white members of the town never talked about her. Many of the black families along the road stated â€Å"they saw the old 4 1 1. Good job on describing the plot of this story. [Monique Sheffield] RACISM, OPPRESSION AND INEQUAL 5 lady high stepping down the highway; sometimes jabbering in a low insistent voice, sometimes singing, sometimes merely gesturing excitedly with her hands. † Country Lovers written by 1975 by Nadine Gordimer was narrated using the third person point of view. The main characters involved in this particular story were Thebedi, Paulus Eysendyck, and Njabulo. Thebedi, a poor black girl, who was 18 years of age, grew up in the Kraal of South Africa working as a farm hand with her father on the property of her childhood friend Paulus Eysendyck. Paulus was a young, white, 19 year old whose father owned the land. Over the years Paulus grew fond of Thebedi. Paulus’ endearment towards Thebedi was illustrated by bringing Thebedi a painted box from when he attended boarding school. Thebedi also showed her affection toward Paulus by giving him a bracelet she had made out of brass wire. The theme of this story is based around the perils of apartheid, segregation and racism. Their actions (Paulus and Thebedi) exemplified the policies of the South African because they carefully, strategically plan their encounters. Njabulo, a bright young black boy who lives in the Kraal also worked on the farm. Njabulo had a secret crush on Thebedi for years, but did not act on it until Paulus entered Veterinary College. It was at this time that Njabulo asked Thebedi’s father for her hand in marriage. It is customary to distribute brides-wealth to the parents of the bride. Two months into their marriage Thebedi gave birth to a baby girl. At this point in the story the narrator uses descriptive literary terms to entice the reader to become fully engaged. The characteristics of the baby girl were design to initiate the climax of the story. It was mention that the infant’s features were as follows. Her complexion was very light with straight fine hair and her eyes were grey flecked with yellow. These features were very inconsistent with those of both parents being Afro-American. Nevertheless, Njabulo made no 5 1 1. You have summarized some of the story, but have not stated anything that supports the theme. [Monique Sheffield] RACISM, OPPRESSION AND INEQUAL 6 complaints. After Paulus returns home for the holidays, the plot thickens or shall I say takes a turn for the worst. To Paulus’ amazement he overheard the house-servants acquiring about getting a reliable substitute to help out now that Thebedi had a baby. At first glance of the infant Paulus struggled with a grimace of tears, anger, and self- pity. After Paulus asked Thebedi if she had been near the main house with the baby; the way she answered him somewhat confused me. The tone of her voice reflected she cared more about him (Paulus) than the baby. Paulus returned a couple days later to revisit Thebedi and the baby. After remaining in the hut for an extended time, Paulus finally left. The next morning Njabulo found the baby to be dead and buried her. After pathological tests were completed, evidence showed intestinal damage not consistent with death by natural causes. This is another point in the story that thickens the plot, and decreases the credibility of both Paulus and Thebedi. Thebedi rendered a statement at the preliminary examination, â€Å"I saw Paulus pouring liquid into the baby’s mouth. † This statement is a blatant paradox. According to Clugston (2010), a paradox is defined as a contradiction. The comparison and contrast aspect of The Welcome Table and Country Lovers falls into the category of racism, segregation, inequality. In order to give proper respect and credit to the author, I will analyze in depth the tools that were used to portray a perfectly painted picture, starting with The Welcome Table. The setting, the style, the vast proportions of literary terms all combined, paints a vivid reenactment of struggles that Afro-Americans have endured for so many years. For many years Alice Walker has played an integral role contributing to the cause of equal rights for minorities, particularly Afro-Americans. Through the use of her expertise, she has instilled in so many that we must never forget the many years of oppression, filled with endless 6 1 2 3 1. or shall I say takes a turn for Some of the language you are using is informal or conversational in style. Academic writing is structured and formal. What may seem appropriate in everyday conversation is not necessarily appropriate for your essay. [Monique Sheffield] 2. me. Unless you are writing a personal opinion or biographical paper, avoid the use of the personal pronouns I, me, and you. They are considered informal in academic writing. For additional information, visit the Ashford Writing Center located in Constellation. Click on Ch 2. 2. [Monique Sheffield] 3. Thebedi rendered a statement at Explain this more. [Monique Sheffield] RACISM, OPPRESSION AND INEQUAL 7 sacrifices and never ending desire to overcome. Furthermore it is of the uttermost importance to continually strive for advancement. Even though the literary work of Country Lovers deals with racism and segregation, it was based on a romantic and intimate encounter of childhood sweethearts. The Welcome Table portrayed, in my opinion, the true struggles which transpired in the days before the abolishment of slavery. I think the tone portrayed in The Welcome Table showed evidence that when read could very well captivate your entire train of thought. The tone that was used in The Welcome Table increased in strength as the story migrated. All the way to the end of the story, I wanted to continue reading, unlike Country Lovers. In my opinion Country Lovers’ tone was not as strong. The settings of both were written in a time where even though laws were passed to ban or revoke discrimination, it was still apparent and practice regularly. One major difference in my opinion was the style of The Welcome Table compared to that of Country Lovers. Even though both literary works are categorized as being told in the third person, The Welcome Table actually changed narrators several times which in my opinion added life and charisma to the story. For example, The Welcome Table narration went from the reverend to the old lady, back to the usher, then to the white woman of the church, to their husbands, and finally back to the elderly woman. Enclosed in my comparison and contrast essay of The Welcome Table and Country Lovers, you will find a descriptive analysis of the similarities and differences between each piece of literature. I also included the theme, plot, style and list of characters that were involved in each piece. I incorporated several literary terms which aided in the development of each story. Throughout my paper, I also described the difference between the tone of the two authors, and how 7

The Biological Effects Of Ionizing Radiation Biology Essay

The Biological Effects Of Ionizing Radiation Biology Essay The biological effects of ionizing radiation are determined by both the radiation dose and the radiation quality ionization density. To understand the radiation protection concerns associated with different types of ionizing radiation, knowledge of both the extent of exposure and consequent macroscopic dose absorbed gray value, as well as the microscopic dose distribution of the radiation modality is required. The definitions of these variables are discussed below but in general to advance the knowledge of the biological effects of different radiation types one needs to know the dose absorbed, the radiation quality and effectiveness of a particular radiation type to induce biological damage. In this study the biological effect of high energy neutrons is compared to that of a reference radiation type 60Co ÃŽÂ ³-rays for a cohort of donors, mostly radiation workers. Comparisons are made at different dose levels in blood cells from each donor to ascertain the relative biological effectiveness of the test radiation modality against that of a recognized reference radiation (Hall, 2005). Such studies are essential to determine the radiation quality for high energy neutron sources applicable to practises in radiation protection. In some nuclear medicine applications radionuclides are used to treat malignant disease. For this the use of short lived alpha particle emitters or other radiation modalities that deliver high ionization densities in cells, are particularly attractive. This as the cellular response in relation to inherent radiosensitivity of the effected cells is thought to be more consistent compared to the use of radionuclides that emit radiation with a lower ionization density e.g. ÃŽÂ ²-particles. The relative biological effectiveness of the high energy neutrons used in this study is followed as a function of the inherent radiosensitivity of different individuals. This allows the identification of cell populations that are relatively sensitive or relatively resistant to radiation. As such research material is available to investigate cellular response too Auger electrons. The latter is known to induce biological damage akin to that of alpha particles. A short description of the physical and biological variables applicable to this study is summarised below. Ionizing Radiation The term ionizing radiation refers to both charged particles (e.g., electrons or protons) and uncharged particles (e.g., photons or neutrons) that can impart enough energy to atoms and molecules to cause ionizations in that medium, or to initiate nuclear or elementary-particle transformations that in turn result in ionization or the production of ionizing radiation. Ionization produced by particles is the process by which one or more electrons are liberated in collisions of the particles with atoms or molecules (The International Commission on Radiation Units and Measurements [ICRU] Report 85, 2011). Interaction of Ionizing Radiation with Matter Ionizing radiation is not restricted to ionization events alone. Several physical and chemical effects in matter such as: heat generation, atomic displacements, excitation of atoms and molecules, destruction of chemical bonds and nuclear reactions may occur. The effects of ionizing radiation on matter depend on the type and energy of radiation, the target, and the irradiation conditions. Radiation can be categorized in terms of how it induces ionizations: Directly ionizing radiation, consist of charged particles such as electrons, protons and alpha particles. Indirectly ionizing radiation consists of neutral particles and/or electromagnetic radiation such as neutrons and photons (ÃŽÂ ³-rays and X-rays). Ionising radiation interacts with matter by: Interaction with the electron cloud of the atom, or by Interaction with the nucleus of the atom. Types of ionizing radiation linked to this study ÃŽÂ ³-rays Ionizing photons (ÃŽÂ ³- and X-rays) are indirectly ionising radiation. These wave like particles have zero rest mass and carry no electrical charge. Low energy (E>2m0c2) may be absorbed by atomic nuclei and initiate nuclear reactions (Cember, 1969). The charged electrons emitted from the atoms, produce the excitation and ionisation events in the absorbing medium. Neutrons Neutrons, similar to ionizing photons are indirectly ionizing radiations; however, these particles do have a rest mass. There is negligible interaction between neutrons and the electron cloud of atoms since neutrons do not have a net electrical charge (Henry, 1969). The principle interactions occur through direct collisions with atomic nuclei during elastic scattering events. In this process, ionisation is produced by charged particles such as recoil nuclei and nuclear reaction products. The production of secondary ionising photons will result in the release of energetic electrons. In turn these charged particles can deposit energy at a considerable distance from the interaction sites (Pizzarello, 1982). Auger electrons Auger electron emission is an atomic-, not a nuclear process. In this process an electron is ejected from an orbital shell of the atom. A preceding event, e.g. electron capture (EC) or internal conversion (IC) leaves the atom with a vacant state in its electron configuration. An electron from a higher energy shell will drop into the vacant state and the energy difference will be emitted as a characteristic x-ray (Cember, 1969). The energy of the x-ray (Ex-ray) being the difference in energy (E) between the two electron shells L and K. Ex-ray = EL -EK Alternatively, the energy may be transferred to an electron of an outer shell, causing it to be ejected from the atom (Fig. 1). The emitted electron is known as an Auger electron and similarly to the x-ray has an energy: EAuger = EΆ -EB where: EΆ = the energy of inner-shell vacancy energy of outer-shell vacancy EB = binding energy of emitted (Auger) electron Auger emission is favoured for, low-Z materials where electron binding energies are small. Auger electrons have low kinetic energies; hence travel only a very short range in the absorbing medium (Cember, 1969). File:Auger Process.svg Fig. 1: Schematic representation of the Auger electron emission process, where an orbital electron is ejected following an ionization event. Dosimetric Quantities Several dosimetric quantities have been defined to quantify energy deposition in a medium when ionizing radiation passes through it. Radiation fields are well described by physical quantities such as particle fluence or air kerma free in air are used. However these quantities do not relate to the effects of exposure on biological systems (International Commission on Radiological Protection [ICRP] Publication 103, 2007). The absorbed dose, D, is the basic physical quantity used in radiobiology, radiology and radiation protection that quantifies energy deposition by any type of radiation in any absorbing material. The International System of Units (SI) of absorbed dose is joule per kilogram (J.kg-1) and is termed the gray (Gy). Absorbed dose, D, is defined as the quotient of mean energy, dÃŽÂ µ, imparted by ionising radiation in a volume element and the mass, dm, of the matter in that volume (Cember, 1969). The absorbed dose quantifies the energy imparted per unit mass absorbing medium, but does not relate this value to radiation damage induced in cells or tissue. The radiation weighted dose (HT) is used as a measure of the biological effect for a specific radiation quality on cells or tissue. It is calculated from equation where DT,R is the mean absorbed dose in a tissue T due to radiation of type R and wR is the corresponding dimensionless radiation weighting factor. The unit of radiation weighted dose is J.kg-1 and is termed the sievert (Sv). Radiation weighting factors are recommended by the International Commission on Radiological Protection (International Commission on Radiological Protection [ICRP] Publication 103, 2007) and are derived from studies on the effect of the micro-deposition of radiation energy in tissue and on its carcinogenic potential. Linear Energy Transfer (LET) Ionizing radiation deposits energy in the form of ionizations along the track of the ionizing particle. The spatial distribution of these ionization events is related to the radiation type. The term linear energy transfer (LET) relates to the rate at which secondary charged particles deposit energy in the absorbing medium per unit distance (keV/ µm). LET is a realistic measure of radiation quality (Duncan, 1977). The LET (L) of charged particles in a medium is defined as the quotient of dE/dl where dE is the average energy locally imparted to the medium by a charged particle of specified energy in traversing a distance dl (Pizzarello, 1982). For high energy photons (x- and ÃŽÂ ³-rays), fast electrons are ejected when energetic photons interact with the absorbing medium. The primary ionization events along the track of the ionizing particle are well separated. This type of sparsely ionizing radiation is termed low-LET radiation. The LET of a 60Cobalt teletherapy source (1.3325 and 1.1732 MeV) is in the range of 0.24 keV/ µm (Vral et al., 1994). Neutrons cause the emission of recoil protons, alpha particles and heavy nuclear fragments during scattering events. These emitted charged particles interact more readily with the absorbing medium and cause densely spaced ionizing events along its track. The p66(Be) neutron beam used in this study has an ionization density of 20 keV/ µm and hence regarded as high-LET radiation. Auger electrons travel very short distances in the absorbing medium due to their low kinetic energies. All the energy of these particles is liberated in small volumes over short track lengths. Ionization densities are therefore very high, up to 40 keV/ µm this is comparable to high-LET alpha particles (Godu et al., 1994). Relative Biological Effectiveness (RBE) The degree of damage caused by ionizing radiation depends firstly on the absorbed dose and secondly on the ionization density or quality of radiation. Variances in the biological effects of different radiation qualities can be described in terms of the relative biological effectiveness (RBE). RBE defines the magnitude of biological response for a certain radiation quality compared to a distinct reference radiation. It is expressed in terms of the ratio (Quoc, 2009): Megavoltage X-rays or 60Co ÃŽÂ ³-rays are commonly employed as the reference radiation since these are standard therapeutic sources of radiation. Thus for an identical dose neutrons the biological effect observed would be greater, compared to 60Co ÃŽÂ ³-rays. The fundamental difference between these radiation modalities is in the spatial orientation or micro deposition of energy. Furthermore, RBE varies as a function of the dose applied increase in RBE is noted for a decrease in dose. By evaluating dose response curves (Fig 2), it is evident that the shoulder of the neutron curve is much shallower (smaller ÃŽÂ ²-value) compared to the reference radiation curve. Therefore changes in RBE are prominent over low dose ranges (Hall, 2005). Fig 2: Dose response curves based on the linear quadratic model demonstrate differences in RBE as a function of dose. Through evaluation of the biological effect curves it is apparent that the RBE for a specific radiation quality may vary. This is characterized by the type of tissue or cells being investigated, dose and dose rates applied oxygenation status of the tissue, energy of radiation and the phase of the cell cycle and inherent radiosensitivity of cells. The RBE increases with a decrease in dose, to reach a maximum RBE denoted RBEM this is calculated from the ratio of the initial slope of the dose response curves for both radiation modalities. RBE LET relationship For a given absorbed dose, differences in the biological response for several cell lines, exposed to different radiation qualities have been demonstrated (Slabbert et al., 1996). Cells exposed to a specified dose low LET radiation do not exhibit the same biological endpoint than those exposed to same dose high LET radiation. This since with low LET radiation a substantial amount of damage may be repaired because the energy density imparted to each ionization site is relatively low. The predominant mode of interaction for this radiation type is indirect through chemical attack from radiolysis of water. As the LET increases, for a specific dose, fewer sites are damaged but the sites that are located along the track of the ionizing particle are severely damaged because more energy is imparted. Thus the probability of direct interaction between the particle track and the target molecule increases with an increase in LET. The RBE of radiation can be correlated with the estimates of LET values. However, as the LET increases, exceeding 10keV/ µm it is no longer possible to assign a single value for the RBE. Beyond this LET, the shape of the cell survival curve changes markedly in the shoulder region compared to low-LET. Since RBE is a measure of the biological effect produced, comparison of the low-LET and high-LET curves will reveal that RBE increases with decreasing dose (Hall, 2005). The average separation in ionizing events at LET of about 100 keV/ÃŽÂ ¼m is equal to the width of deoxyribonucleic acid (DNA) double strand molecule (Fig. 3). Further increase in LET results in decreased RBE since ionization events occur at smaller intervals than DNA molecule strand separation (Fig. 3) and this energy imparted does not contribute to DNA damage. Fig 3: Average spatial distribution of ionizing events for different LET values in relation to the DNA double helix structure (Hall 2005). Cellular Radiosensitivity Tissue radiosensitivity models In 1906 the radiobiologists Bergonie and Tribondeau established a rule for tissue radiosensitivity. They studied the relative radiosensitivities of cells and from this could predict which type of cells would be more radiosensitive (Hall, 2005). Bergonie and Tribondeau realized that cells were most sensitive to radiation when they are: Rapidly dividing (high mitotic activity). Cells with a long dividing future. Cells of an unspecialised type. The law of Bergonie and Tribondeau was later adapted by Ancel and Vitemberger; they concluded that radiation damage is dependent on two factors: the biological stress on the cell. the conditions to which the cell is exposed pre and post irradiation. Cell division causes biological stress thus cells with a short doubling time express radiation damage at an earlier stage than slowly dividing cells. Undifferentiated rapidly dividing cells therefore are most radiosensitive (Hall, 2005). A comprehensive system of classification was proposed by Rubin and Casarett, cell populations were grouped into 4 categories based on the reproduction kinetics: Vegetative intermitotic cells were defined as rapidly dividing undifferentiated cells. These cells usually have a short life cycle. For example: erythroblasts and intestinal crypt cells and are very radiosensitive. Differentiating intermitotic cells are characterized as actively dividing cells with some level of differentiation. Examples include: meylocytes and midlevel cells in maturing cell lines these cells are radiosensitive. Reverting postmitotic cells are regarded as to not divide regularly and generally long lived. Liver cells is an example of this cell type, these cell types exhibit a degree radioresistance. Fixed postmitotic cells do not divide. Cells beloning to this classification are regarded to be highly differentiated and highly specialized in both morphology and function. These cells are replaced by differentiating cells in the cell maturation lines and are regarded as the most radioresistant cell types. Nerve and muscle cells are prime examples (Hall, 2005). Michalowski proposed a type of classification which divides tissues into hierarchical (H-type) and flexible (F-type) populations. Within this classification cells are grouped in 3 distinct categories: Stem cells, that continuously divide and reproduce to give rise to both new stem cells and cells that eventually give rise to mature functional cells. Maturing cells arising from stem cells and through progressive division eventually differentiate into an end-stage mature functional cell. Mature adult functional cells that do not divide Examples of H-type populations include the bone marrow, intestinal epithelium and epidermis; these cells are capable of unlimited proliferation. In F-type populations the adult cells can under certain circumstance be induced to undergo division and reproduce another adult cell. Examples include; liver parenchymal cells and thyroid cells. The two types represent the extremes in cell populations. It should be noted that most tissue populations exist between the extremes, these exhibit characteristics of both types where mature cells are able to divide a limited number of times. The sensitivity to radiation can be attributed to the length of the life cycle and the reproductive potential of the critical cell line within that tissue (Hall, 2005). Cell cycle dependent radiosensitivity As cells progress through the cell cycle various physical and biochemical changes occur (Fig. 4). These changes influence the response of cells to ionizing radiation. Variations in radiosensitivity for several cell types at different stages of the cell cycle has been documented (Hall, 2005). Following the law of Bergonie and Tribondeau that cells with high mitotic activity are most radiosensitive, it was found that cells in the mitotic phase (M-phase) of the cell cycle are most sensitive. Late stage gap 2 (G2) phase cells are also very sensitive with gap 1 (G1) phase being more radioresistant and synthesis (S phase) cells the most resistant (Domon, 1980). Fig. 4: Cell cycle of proliferating cells representing the different phases leading up to cell division. The G0 resting phase for cells that do not actively proliferate has been included since T-lymphocytes naturally occur in this phase (Hall, 2005). Nonproliferating cells, generally cells that are fully differentiated, may enter the rest phase G0 from G1 and remain inactive for long periods of time. Peripheral T-lymphocytes seldom replicate naturally and remain in G0 indefinately. Lymphocyte Radiosensitivity The hematopoietic system is very sensitive to radiation. Differential blood analyses are routinely employed as a measure of radiation exposure. This measurement is based on the sensitivity of stem cells and the changes observed in the constituents of peripheral blood due to variations in transit time from stem cell to functioning cell (Hall, 2005). It has been shown that lymphocytes, although they are resting cells (G0 phase) which do not actively proliferate nor do have a long dividing future hence do not meet the criteria of a radiosensitive cell type as described above are of the most radio sensitive cells. The reasons for their acute sensitivity cannot be explained (Hall, 2005). Furthermore two distinct subpopulations T-lymphocytes with respect to radiosensitivity were found in peripheral blood. The small T-lymphocyte which is extremely radiosensitive and disappears almost completely from the peripheral blood at doses of 500 mGy (Kataoka, 1974, Knox, 1982 and Hall, 2005). Cytogenetic expression of ionizing radiation induced damage The primary target in radiotherapy is the double helix deoxyribonucleic acid (DNA) molecule (Rothkam et al. 2009). This macro molecule contains the genetic code critical to the development and functioning of most living organisms. The DNA molecule consists of two strands held together by hydrogen bonds between the bases. Each strand is made up of four types of nucleotides. A nucleotide consists of a five-carbon sugar (deoxyribose), a phosphate group and a nitrogen containing base. The nitrogen containing bases are adenine, guanine, thymine or cytosine. Base pairing between two nucleotide strands is universally constant with adenine pairing with thymine and guanine with cytosine (Fig. 5). This attribute permits effective single strand break repair since the opposite strand is used as a template during the repair process. The base sequence within a nucleotide strand differs; the arrangement of bases defines the genetic code. The double helix DNA molecule is wound up on histones and bou nd together by proteins to form nucleosomes. This structure is folded and coiled repeatedly to become a chromosome. Fig. 5: The double helix structure of a DNA molecule consists of two neucleotide strands held together by hydrogen bonds between the bases. Figure modified from http://evolution.berkeley.edu/evolibrary/article/history_22 by P Beukes. Ionizing radiation can either interact directly or indirectly with the DNA strand. When an ionization event occurs in close proximity to the DNA molecule direct ionization can denature the strand. Ionization events that occur within the medium surrounding the DNA produce free radicals such as hydrogen peroxide through radiolysis of water. Damage induced by ionizing radiation to the DNA include base damage (BD), single strand breaks (SSB), abasic sites (AS), DNA-protein cross-links (DPC), and double strand breaks (DSB) (Fig. 6). Fig. 6: Examples of several radiation induced DNA lesions. Figure modified from Best B (9) by P Beukes. Low-LET radiation primarily causes numerous single strand breaks, through direct and indirect interaction (Hall, 2005). Single strand breaks are of lesser biological importance since these are readily repaired by using the opposite strand as a template. High-LET radiation damage is dominated by direct interactions with the DNA molecule. Densely ionizing radiation has a greater probability to induce irreparable or lethal double strand breaks since energy deposition occurs in discrete tracks (Hall, 2005). The number of tracks will be fewer but more densely packed compared to low-LET radiation of equivalent doses. Several techniques to quantify chromosomal damage and chromatid breaks have been established. These range from isolating DNA and passing it through a porous substrate or gel (Hall, 2005) by applying an external potential difference too advanced techniques of visually observing and numerating chromosomal aberrations of interphase cells. Cytogenetic chromosome aberration assays of peripheral blood T-lymphocytes to assess radiation damage include but are not limited to: premature chromosome condensation (PCC) assay, metaphase spread dicentric and ring chromosome aberration assay (DCA), metaphase spread fluorescence in situ hybridisation (FISH) translocation assay and cytokinesis blocked micronuclei (CBMN) assay (Fig. 7). Fig. 7: Different cytogenetic assays on peripheral T-lymphocytes for use in biological dosimetry. Figure modified from Cytogenetic Dosimetry IAEA, 2011. PCC occurs when an interphase cell is fused with a mitotic cell. The fusion causes the interphase cell to produce condensed chromosomes prematurely. Chromosomal aberrations can thus be analysed immediately following irradiation without the need for mitogen stimulation or cell culturing. Numeration of dicentrics in metaphase spreads has been used with great success to assess radiation damage in cells since the 1960s (Vral et al, 2010). The incidence of these aberrations follows a linear quadratic function with respect to the dose. Unstable aberrations like dicentrics or centric rings are lethal to the cell hence not passed on to daughter cells (Hall, 2005). In contrast translocations are stable aberrations; these are not lethal to the cell and passed on to daughter cells. Examination of translocations thus provides a long term history of exposure. Although the abovementioned techniques are very accurate and well described, the complexity and time consuming nature of the assays has stimulated the development of automated methods of measuring chromosomal damage. Micronuclei (MN) formation in peripheral blood T-lymphocytes lends itself to automation, since the outcome of radiation insult is visually not too complex with limited variables. DNA damage incurred from ionizing radiation or chemical clastogens induce the formation of acentric chromosome fragments and to a small extent malsegregation of whole chromosomes. Acentric chromosome fragments and whole chromosomes that are unable to engage with the mitotic spindle lag behind at anaphase (Cytogenetic Dosimetry IAEA, 2011). Micronuclei originate from these acentric chromosome fragments or whole chromosomes which are excluded from the main nuclei during the metaphase/anaphase transition of mitosis. The lagging chromosome fragment or whole chromosome forms a small separate nucleus visible in the cytoplasm of the cell. Image recognition software can thus be employed to quantify radiation damage by applying classifiers that describe cell size, staining intensity, cell separation, aspect ratio and cell characteristics when numerating MN frequency in BN cells. The classifiers are fully customizable depending on cell size, staining technique or cell type that will be used. Rationale for this study The principal objective of this study is to define RBE variations for high-LET radiation with respect to radiosensitivity. Specifically this is done for very high energy neutrons and Auger electrons. In general the response of different cell types vary much more to treatment with low-LET radiation compared to high-LET radiation (Broerse et al. 1978). Radiosensitivity differences have been demonstrated for different cancer cell lines (Slabbert et al. 1996) as well as various clonogenic mammalian cells (Hall, 2005) exposed to both high and low-LET radiation. In general there is an expectation and in certain cases some experimental evidence to support less variations in radiosensitivities of cells to high-LET radiation. Furthermore the ranking in the relative radiosensitivity of cell types changed for neutron treatments compared to exposure to X-rays (Broerse et al. 1978). To quantify the radiation risk of individuals exposed to cosmic rays or mixed radiation fields of neutrons and ÃŽÂ ³-rays, several experiments were conducted to ascertain biological damage induced by neutron beams of various energies (Nolte et al., 2007). Clonogenic survival data (Hall, 2005), dicentric chromosome aberrations (Heimers 1994) and micronuclei formation (Slabbert et. al 2010) have been followed. Chromosome aberration frequencies have been quantified and this represent radiation risk to neutron energies ranging from 36 keV up to 14.6 MeV (Schmid et al. 2003). To complement these studies additional measurements have been made for blood cells exposed to 60 MeV and 192 MeV quasi monoenergetic neutron beams (Nolte et al. 2007). Comparisons of RBE values obtained in these studies are shown in figure 1. Significant changes in the maximum relative biological effectiveness (RBEM) of these neutron sources are demonstrated as a function of neutron energy, with a maximum value of 90 at 0.4 MeV. RBEM drop to  ±15 for neutron energies higher than 10 MeV and it appears that the RBEM remain constant up to 200 MeV. The RBEM value of 47 -113 reported by Heimers et al. (1999) is not consistent with these observations. Fig. 1: RBEM values for neutrons of different energies after Nolte et al. (2007) The data shown in Fig. 1 was obtained by using the blood of a single donor. This to ensure consistency in the biological response for different neutron energies used in different radiation facilities in different parts of the world. Keeping the donor constant has the advantage that only a single data set for the reference radiation was needed. These measurements were done over several years. In all these studies, dicentric chromosome aberrations were followed. As informative as these investigations may be, it is doubtful if RBE values obtained from blood samples from a single donor are indeed representative for the wider population to state radiation weighting factors. It is unclear if RBE values for high energy neutrons will vary when measured with cells with different inherent radiosensitivities. Warenius et al. (1994) demonstrated that the RBE of a 62.5 MeV neutron beam increases with increase in radioresistance to 6 MV X-rays. Similarly Slabbert et al (1996) using a 29 MeV p(66)/Be neutron with an average energy of 29 MeV, noted a statistically significant increase in the RBE values for cell types with increased radioresistance to 60Co ÃŽÂ ³-rays. Although these investigators used 11 different cell types, few of these were indeed radioresistant to 60Co ÃŽÂ ³-rays. Close inspection of the data shows that the relationship between neutron RBE and radioresistance to photons disappear when the cell type with the highest resistance to ÃŽÂ ³-rays (Gurney melanoma) is removed from the data set Slabbert et al. 1996). In a follow up study the authors failed to demonstrate the relationship for a p(66)/Be neutron beam but such a relationship was demonstrated for a d14/Be neutron beam (Slabbert et al. 2000). It therefore appears that the relationship for RBE and radioresistance is dependent on the selection of cells used in the study as well as the neutron energy. Using lymphocytes Vral et al. (1994) demonstrated a clear reduction RBEM values for 5,5 MeV neutrons with an increase in the ÃŽÂ ±-values of dose effect curves obtained for 60Co ÃŽÂ ³-rays. This for lymphocytes obtained from six healthy donors. Using only four donors Slabbert et al. (2010) also demonstrated a relationship between RBEM neutrons and radiosensitivity to 60Co y rays. In the latter case the RBEM values are lower as can be expected since these investigators used a higher energy neutron source. Although a significant relationship between these parameters has been demonstrated by the investigators, the cohort of 4 donors in the study is very small. In fact 2 out of the 4 donors have different RBEM values but appear to have the same radiosensitivity. A study using larger number of donors with blood cells exposed to high energy neutrons is clearly needed. This in particular too verify the findings above indicating a different wR for donors of different sensitivity. The studies of RBE variations with neutron energy by Schmid et al., (2003), Nolte et al. (2005) and were conducted dicentric formations observed in metaphase spreads. It is known that more than six months were used to analyse the data for different doses for blood cells obtained from a single donor exposed to a single neutron energy. It follows that some method of automation to assist the radiobiological evaluation of cellular radiation damage is needed to quantify wR values as a function of radiosensitivity. Recently a semi-automated image analysis system, Metafer 4, this holds promise to test numerous donors for micronuclei formations Study to include more participants hence Metaferà ¢Ã¢â€š ¬Ã‚ ¦.